Motif ID: ELK1,4_GABP{A,B1}.p3

Z-value: 5.144


Transcription factors associated with ELK1,4_GABP{A,B1}.p3:

Gene SymbolEntrez IDGene Name
ELK1 2002 ELK1, member of ETS oncogene family
ELK4 2005 ELK4, ETS-domain protein (SRF accessory protein 1)
GABPA 2551 GA binding protein transcription factor, alpha subunit 60kDa
GABPB1 2553 GA binding protein transcription factor, beta subunit 1



Activity profile for motif ELK1,4_GABP{A,B1}.p3.

activity profile for motif ELK1,4_GABP{A,B1}.p3


Sorted Z-values histogram for motif ELK1,4_GABP{A,B1}.p3

Sorted Z-values for motif ELK1,4_GABP{A,B1}.p3



Network of associatons between targets according to the STRING database.



First level regulatory network of ELK1,4_GABP{A,B1}.p3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr20_-_49008445 11.083 NM_003859
DPM1
dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit
chr2_-_152740387 9.254 NM_005843
STAM2
signal transducing adaptor molecule (SH3 domain and ITAM motif) 2
chr20_+_21231921 7.617 NM_012255
XRN2
5'-3' exoribonuclease 2
chr20_+_49008754 7.061 NM_014484
MOCS3
molybdenum cofactor synthesis 3
chr20_+_60395515 6.791 NM_001024
RPS21
ribosomal protein S21
chr6_+_111409933 6.577 NM_032194
RPF2
ribosome production factor 2 homolog (S. cerevisiae)
chr2_-_27147995 6.265 NM_001134693
OST4
oligosaccharyltransferase 4 homolog (S. cerevisiae)
chr2_-_73817935 6.239 NM_016058
TPRKB
TP53RK binding protein
chr12_+_118590039 6.063 NM_006253
PRKAB1
protein kinase, AMP-activated, beta 1 non-catalytic subunit
chr2_+_220170804 5.727 NM_052902
STK11IP
serine/threonine kinase 11 interacting protein
chr1_-_28842103 5.498 NM_001135218
NM_005644
TAF12

TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa

chr17_-_53784494 5.439 NM_003168
SUPT4H1
suppressor of Ty 4 homolog 1 (S. cerevisiae)
chr6_+_30693464 5.355 NM_014046
MRPS18B
mitochondrial ribosomal protein S18B
chr2_+_176842368 5.343 NM_006554
MTX2
metaxin 2
chr2_-_20413838 5.272 PUM2
pumilio homolog 2 (Drosophila)
chr2_-_201461945 5.268 NM_032472
NM_130906
PPIL3

peptidylprolyl isomerase (cyclophilin)-like 3

chr2_+_32244406 5.168 NM_001193513
NM_001193514
NM_001193515
NM_017964
SLC30A6



solute carrier family 30 (zinc transporter), member 6



chr3_-_130600931 5.138 RPL32P3
ribosomal protein L32 pseudogene 3
chr2_-_54051290 5.113 NM_014614
PSME4
proteasome (prosome, macropain) activator subunit 4
chr1_+_232575850 4.996 NM_001012985
C1orf31
chromosome 1 open reading frame 31
chr14_-_23781607 4.920 NM_001099274
NM_012461
TINF2

TERF1 (TRF1)-interacting nuclear factor 2

chr21_-_29286982 4.916 NM_015565
LTN1
listerin E3 ubiquitin protein ligase 1
chr6_-_119137923 4.915 NM_001178035
C6orf204
chromosome 6 open reading frame 204
chr12_-_104153920 4.886 NM_018171
APPL2
adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2
chr11_-_17055763 4.847 NM_001017
RPS13
ribosomal protein S13
chr17_-_53282376 4.839 NM_016070
MRPS23
mitochondrial ribosomal protein S23
chr16_-_11852862 4.805 NM_015659
RSL1D1
ribosomal L1 domain containing 1
chr12_-_48248132 4.780 NM_006337
MCRS1
microspherule protein 1
chr14_-_23781328 4.755 TINF2
TERF1 (TRF1)-interacting nuclear factor 2
chr20_+_60395623 4.694 RPS21
ribosomal protein S21
chr4_-_4300821 4.679 NM_032927
TMEM128
transmembrane protein 128
chr15_+_72620570 4.655 NM_006465
ARID3B
AT rich interactive domain 3B (BRIGHT-like)
chr1_+_22224571 4.638 HSPC157
hypothetical LOC29092
chr17_-_53950191 4.622 NM_004687
MTMR4
myotubularin related protein 4
chr17_-_44377094 4.619 NM_007241
SNF8
SNF8, ESCRT-II complex subunit, homolog (S. cerevisiae)
chr2_+_201462294 4.615 NM_001136039
NM_001142355
NM_021824
NIF3L1


NIF3 NGG1 interacting factor 3-like 1 (S. pombe)


chr12_-_119116848 4.607 NM_006836
GCN1L1
GCN1 general control of amino-acid synthesis 1-like 1 (yeast)
chr7_+_107171809 4.581 CBLL1
Cas-Br-M (murine) ecotropic retroviral transforming sequence-like 1
chr20_-_5041482 4.573 NM_001009923
NM_001009924
NM_001009925
NM_014145
C20orf30



chromosome 20 open reading frame 30



chr20_-_44426407 4.555 NM_015945
NM_173073
NM_173179
SLC35C2


solute carrier family 35, member C2


chr20_+_18496068 4.525 LOC388789
hypothetical LOC388789
chr2_+_97628929 4.511 NM_001862
COX5B
cytochrome c oxidase subunit Vb
chr15_+_32304477 4.478 NM_016454
TMEM85
transmembrane protein 85
chr16_+_68938264 4.467 NM_018332
DDX19A
DEAD (Asp-Glu-Ala-As) box polypeptide 19A
chr14_+_34521945 4.424 SRP54
signal recognition particle 54kDa
chr14_-_38709161 4.358 NM_001079537
NM_177452
TRAPPC6B

trafficking protein particle complex 6B

chr16_+_21926939 4.354 NM_001164579
C16orf52
chromosome 16 open reading frame 52
chr20_+_43478120 4.353 NM_001184728
NM_001184729
NM_001184730
NM_015937
PIGT



phosphatidylinositol glycan anchor biosynthesis, class T



chr10_-_15942461 4.271 NM_024948
FAM188A
family with sequence similarity 188, member A
chr20_-_2592777 4.270 NM_006899
NM_174855
NM_174856
IDH3B


isocitrate dehydrogenase 3 (NAD+) beta


chr7_-_44496703 4.225 NM_015332
NUDCD3
NudC domain containing 3
chr6_+_170705345 4.210 NM_001172085
NM_003194
TBP

TATA box binding protein

chr20_+_3138055 4.208 NM_033453
NM_181493
ITPA

inosine triphosphatase (nucleoside triphosphate pyrophosphatase)

chr14_+_34521854 4.172 NM_001146282
NM_003136
SRP54

signal recognition particle 54kDa

chr21_+_42807052 4.157 SLC37A1
solute carrier family 37 (glycerol-3-phosphate transporter), member 1
chr20_+_33750645 4.126 NM_080748
ROMO1
reactive oxygen species modulator 1
chr6_-_28327980 4.119 NM_019110
ZKSCAN4
zinc finger with KRAB and SCAN domains 4
chr16_+_79132354 4.100 NM_130897
DYNLRB2
dynein, light chain, roadblock-type 2
chr16_-_3601580 4.057 NM_032444
SLX4
SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae)
chr14_+_23937766 4.044 NM_025081
NYNRIN
NYN domain and retroviral integrase containing
chr6_+_10803141 4.017 NM_017906
PAK1IP1
PAK1 interacting protein 1
chr14_+_73423260 3.978 NM_021188
ZNF410
zinc finger protein 410
chr2_-_122210873 3.934 NM_032390
MKI67IP
MKI67 (FHA domain) interacting nucleolar phosphoprotein
chr10_+_112247614 3.906 NM_004419
DUSP5
dual specificity phosphatase 5
chr2_+_128565269 3.883 UGGT1
UDP-glucose glycoprotein glucosyltransferase 1
chr16_-_15095590 3.875 NM_018427
RRN3
RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae)
chr16_+_8799170 3.833 NM_000303
PMM2
phosphomannomutase 2
chr20_+_28225511 3.829 LOC283788
FRG1B
FSHD region gene 1 pseudogene
FSHD region gene 1 family, member B
chr17_-_59923547 3.816 NM_007215
POLG2
polymerase (DNA directed), gamma 2, accessory subunit
chr14_+_23771464 3.816 NM_001002000
NM_001002001
GMPR2

guanosine monophosphate reductase 2

chr5_-_114626422 3.750 NM_005023
PGGT1B
protein geranylgeranyltransferase type I, beta subunit
chr1_-_220829704 3.725 NM_005681
NM_139352
TAF1A

TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa

chr16_+_2593351 3.685 LOC652276
hypothetical LOC652276
chr6_+_30142910 3.652 NM_021959
PPP1R11
protein phosphatase 1, regulatory (inhibitor) subunit 11
chr17_+_43328514 3.635 NM_003110
SP2
Sp2 transcription factor
chr6_-_33398656 3.622 NM_001141969
NM_001141970
NM_001350
DAXX


death-domain associated protein


chr2_-_24995402 3.622 NM_004036
ADCY3
adenylate cyclase 3
chr17_+_72596349 3.612 SEC14L1
C17orf86
SEC14-like 1 (S. cerevisiae)
chromosome 17 open reading frame 86
chr3_+_180348818 3.611 NM_006218
PIK3CA
phosphoinositide-3-kinase, catalytic, alpha polypeptide
chr2_-_74915722 3.610


chr2_+_198026470 3.607 NM_025147
COQ10B
coenzyme Q10 homolog B (S. cerevisiae)
chr12_+_67366989 3.594 NM_020401
NUP107
nucleoporin 107kDa
chr17_-_38229790 3.558 NM_003766
BECN1
beclin 1, autophagy related
chr20_-_33750457 3.549 NM_001198989
NM_021100
NFS1

NFS1 nitrogen fixation 1 homolog (S. cerevisiae)

chr2_+_69974581 3.544 NM_006857
SNRNP27
small nuclear ribonucleoprotein 27kDa (U4/U6.U5)
chr6_-_170735593 3.494 NM_002598
NM_144781
PDCD2

programmed cell death 2

chr2_+_65308332 3.487 NM_001005386
NM_005722
ACTR2

ARP2 actin-related protein 2 homolog (yeast)

chr7_+_102775309 3.483 NM_002803
PSMC2
proteasome (prosome, macropain) 26S subunit, ATPase, 2
chr1_-_234834410 3.482 NM_018072
HEATR1
HEAT repeat containing 1
chr2_-_190336168 3.464 NM_022353
OSGEPL1
O-sialoglycoprotein endopeptidase-like 1
chr11_-_117628211 3.458 NM_198275
MPZL3
myelin protein zero-like 3
chr3_-_172660545 3.399 NM_001161560
NM_001161561
NM_001161562
NM_001161563
NM_001161564
NM_001161565
NM_001161566
NM_015028
TNIK







TRAF2 and NCK interacting kinase







chr2_-_45691887 3.390 NM_018079
SRBD1
S1 RNA binding domain 1
chr16_+_23560187 3.390 NM_001199011
NM_032486
DCTN5

dynactin 5 (p25)

chr6_+_139136349 3.370 NM_015439
CCDC28A
coiled-coil domain containing 28A
chr6_+_33530297 3.370 NM_152735
ZBTB9
zinc finger and BTB domain containing 9
chr8_-_22582526 3.362 NM_018688
BIN3
bridging integrator 3
chr14_-_22127902 3.314 DAD1
defender against cell death 1
chr13_-_36531568 3.310 NM_001014286
NM_017569
FAM48A

family with sequence similarity 48, member A

chr16_-_23559978 3.283 NM_024675
PALB2
partner and localizer of BRCA2
chr2_-_68332985 3.281 NM_000945
PPP3R1
protein phosphatase 3, regulatory subunit B, alpha
chr4_+_109761170 3.280 NM_000995
NM_033625
RPL34

ribosomal protein L34

chr2_-_175741096 3.273 NM_001880
ATF2
activating transcription factor 2
chr11_-_57054756 3.267 NM_012456
TIMM10
translocase of inner mitochondrial membrane 10 homolog (yeast)
chr2_-_241690365 3.250 NM_182501
MTERFD2
MTERF domain containing 2
chr17_+_70520339 3.217 NM_001545
ICT1
immature colon carcinoma transcript 1
chr13_+_52124831 3.197 NM_001130912
NM_006704
SUGT1

SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae)

chr2_-_65308220 3.195 LOC729324
hCG1986447
chr20_+_16658608 3.195 NM_003092
NM_198220
SNRPB2

small nuclear ribonucleoprotein polypeptide B

chr16_-_8798973 3.193 NM_015421
TMEM186
transmembrane protein 186
chr7_+_104959767 3.186 NM_021930
RINT1
RAD50 interactor 1
chr1_+_109036431 3.172 NM_018061
PRPF38B
PRP38 pre-mRNA processing factor 38 (yeast) domain containing B
chr17_-_39447817 3.168 NM_032376
TMEM101
transmembrane protein 101
chr3_-_130362563 3.165 NM_020701
ISY1
ISY1 splicing factor homolog (S. cerevisiae)
chr7_+_50318801 3.165 IKZF1
IKAROS family zinc finger 1 (Ikaros)
chr16_+_24648446 3.151 NM_014494
TNRC6A
trinucleotide repeat containing 6A
chr2_-_20053256 3.135 NM_001006657
NM_020779
WDR35

WD repeat domain 35

chr1_+_220884257 3.133 MIA3
melanoma inhibitory activity family, member 3
chr7_-_91713044 3.133 NM_004912
NM_001013406
NM_194454
KRIT1


KRIT1, ankyrin repeat containing


chr3_+_180548173 3.022 NM_033540
MFN1
mitofusin 1
chr12_+_122652572 3.000 NM_020936
DDX55
DEAD (Asp-Glu-Ala-Asp) box polypeptide 55
chr1_-_3702908 2.990 NM_020710
LRRC47
leucine rich repeat containing 47
chr21_+_36614347 2.984 NM_015358
MORC3
MORC family CW-type zinc finger 3
chr20_-_472335 2.982 NM_001895
NM_177559
NM_177560
CSNK2A1


casein kinase 2, alpha 1 polypeptide


chr1_+_23990228 2.981 NM_007260
LYPLA2
lysophospholipase II
chr20_+_61760084 2.980 NM_016434
NM_032957
RTEL1

regulator of telomere elongation helicase 1

chr14_-_21049204 2.975 NM_019852
METTL3
methyltransferase like 3
chr3_+_44571600 2.972 NM_018651
NM_025169
ZNF167

zinc finger protein 167

chr9_-_124733599 2.965 NM_020924
ZBTB26
zinc finger and BTB domain containing 26
chr14_+_23771942 2.962 NM_001002002
NM_016576
GMPR2

guanosine monophosphate reductase 2

chr11_-_71501385 2.953 NM_014042
C11orf51
chromosome 11 open reading frame 51
chr4_+_110956360 2.948 GAR1
GAR1 ribonucleoprotein homolog (yeast)
chr1_-_53458822 2.935 NM_017887
C1orf123
chromosome 1 open reading frame 123
chr16_-_79668304 2.926 NM_001100873
NM_152337
C16orf46

chromosome 16 open reading frame 46

chr12_-_47698781 2.923 NM_002733
NM_212461
PRKAG1

protein kinase, AMP-activated, gamma 1 non-catalytic subunit

chr2_+_74535700 2.922 NM_031288
INO80B
INO80 complex subunit B
chr7_+_6583560 2.922 NM_001134387
NM_001134388
NM_001134389
NM_018106
ZDHHC4



zinc finger, DHHC-type containing 4



chr10_-_51293220 2.889 NM_006327
TIMM23
TIMM23B
translocase of inner mitochondrial membrane 23 homolog (yeast)
translocase of inner mitochondrial membrane 23 homolog B (yeast)
chr10_-_51041156 2.861 NM_003631
AGAP8
LOC728407
PARG
ArfGAP with GTPase domain, ankyrin repeat and PH domain 8
poly(ADP-ribose) glycohydrolase pseudogene
poly (ADP-ribose) glycohydrolase
chr5_+_69381105 2.860 NM_000344
NM_022874
NM_017411
NM_022875
NM_022876
NM_022877
SMN1

SMN2



survival of motor neuron 1, telomeric

survival of motor neuron 2, centromeric



chr4_+_56509793 2.837 NM_025009
CEP135
centrosomal protein 135kDa
chr2_+_239000395 2.833 ASB1
ankyrin repeat and SOCS box containing 1
chr2_-_131567458 2.825 NM_001009993
FAM168B
family with sequence similarity 168, member B
chr1_+_39229474 2.823 NM_001136275
NM_024595
AKIRIN1

akirin 1

chr3_+_32701663 2.798 NM_015442
CNOT10
CCR4-NOT transcription complex, subunit 10
chr6_-_10802823 2.797 NM_001145020
C6orf52
chromosome 6 open reading frame 52
chr16_-_70400232 2.792 AP1G1
adaptor-related protein complex 1, gamma 1 subunit
chr2_+_48395271 2.789 NM_002158
FOXN2
forkhead box N2
chr12_+_56424930 2.770 NM_005981
TSPAN31
tetraspanin 31
chr10_-_18980512 2.759 NM_182543
NSUN6
NOP2/Sun domain family, member 6
chr20_-_57040700 2.757 NM_006886
NM_001001977
ATP5E

ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit

chr4_-_13238368 2.742 NM_148894
BOD1L
biorientation of chromosomes in cell division 1-like
chr5_-_159778621 2.734 NM_006425
SLU7
SLU7 splicing factor homolog (S. cerevisiae)
chr7_+_39572396 2.730 NM_020192
C7orf36
chromosome 7 open reading frame 36
chr9_-_133141726 2.729 NM_033387
FAM78A
family with sequence similarity 78, member A
chr9_+_36562844 2.726 NM_014791
MELK
maternal embryonic leucine zipper kinase
chr3_+_144203061 2.716 NM_001080415
U2SURP
U2 snRNP-associated SURP domain containing
chr5_+_74098828 2.715 NM_014886
NSA2
NSA2 ribosome biogenesis homolog (S. cerevisiae)
chr2_+_118562499 2.714 NM_016133
INSIG2
insulin induced gene 2
chr6_+_41714171 2.711 NM_005586
MDFI
MyoD family inhibitor
chr7_-_32496497 2.706 NM_012322
LSM5
LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr1_+_229731021 2.682 NM_005999
TSNAX-DISC1
TSNAX
TSNAX-DISC1 read-through gene
translin-associated factor X
chr1_+_45926433 2.677 NM_016486
TMEM69
transmembrane protein 69
chr2_+_113058642 2.670 CHCHD5
coiled-coil-helix-coiled-coil-helix domain containing 5
chr8_-_120914233 2.663 NM_003184
TAF2
TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa
chr11_-_13441294 2.653 NM_032320
BTBD10
BTB (POZ) domain containing 10
chr2_+_27659396 2.653 NM_032434
ZNF512
zinc finger protein 512
chr2_+_3362449 2.644 NM_016030
TTC15
tetratricopeptide repeat domain 15
chr1_+_172104115 2.637 NM_001122770
NM_032522
ZBTB37

zinc finger and BTB domain containing 37

chr17_-_74990157 2.635 NM_001082575
RBFOX3
RNA binding protein, fox-1 homolog (C. elegans) 3
chr14_-_38971370 2.634 NM_203301
FBXO33
F-box protein 33
chr1_-_32888677 2.631 NM_178547
ZBTB8OS
zinc finger and BTB domain containing 8 opposite strand
chr2_+_100985122 2.627 NM_000993
NM_001098577
NM_001099693
RPL31


ribosomal protein L31


chr2_+_27740254 2.601 SLC4A1AP
solute carrier family 4 (anion exchanger), member 1, adaptor protein
chr11_+_8660913 2.598 RPL27A
ribosomal protein L27a
chr8_+_11179724 2.593 MTMR9
myotubularin related protein 9
chr12_+_49080858 2.562 NM_001170803
NM_001170804
NM_001170808
NM_052879
NM_199188
NM_199190
LARP4





La ribonucleoprotein domain family, member 4





chr2_-_240724373 2.557 NM_001163424
NM_138336
MYEOV2

myeloma overexpressed 2

chr16_+_2672527 2.548 KCTD5
potassium channel tetramerisation domain containing 5
chr2_+_122124034 2.545 LOC254128
hypothetical LOC254128
chr2_-_197883569 2.544 ANKRD44
ankyrin repeat domain 44
chr1_+_212520899 2.519 NM_020197
SMYD2
SET and MYND domain containing 2
chr4_-_84595967 2.517 NM_133636
HELQ
helicase, POLQ-like
chr14_-_22127954 2.513 NM_001344
DAD1
defender against cell death 1
chr14_+_22368942 2.509 MRPL52
mitochondrial ribosomal protein L52
chr20_-_5879036 2.507 NM_015939
TRMT6
tRNA methyltransferase 6 homolog (S. cerevisiae)
chr16_-_82778071 2.506 NM_005679
NM_139353
TAF1C

TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa

chr14_+_20527971 2.506 METTL17
methyltransferase like 17
chr6_+_32034559 2.502 NM_006929
SKIV2L
superkiller viralicidic activity 2-like (S. cerevisiae)
chr17_-_975809 2.499 ABR
active BCR-related gene
chr4_+_84596141 2.498 NM_016067
MRPS18C
mitochondrial ribosomal protein S18C
chr15_+_48503860 2.492 NM_001128610
NM_001128611
NM_005154
USP8


ubiquitin specific peptidase 8


chr20_-_31452991 2.474 NM_016082
NM_016408
CDK5RAP1

CDK5 regulatory subunit associated protein 1

chr11_+_61647990 2.474 NM_001040694
NM_020238
INCENP

inner centromere protein antigens 135/155kDa

chr1_-_38228179 2.468 NM_006802
SF3A3
splicing factor 3a, subunit 3, 60kDa
chr17_+_42355492 2.454 GOSR2
golgi SNAP receptor complex member 2
chr17_+_35629080 2.453 NM_133264
WIPF2
WAS/WASL interacting protein family, member 2
chr14_-_23981493 2.452 NM_020195
SDR39U1
short chain dehydrogenase/reductase family 39U, member 1
chr20_+_47862782 2.439 SLC9A8
solute carrier family 9 (sodium/hydrogen exchanger), member 8
chr2_+_98591516 2.437 UNC50
unc-50 homolog (C. elegans)

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
2.11 1.18e-17 GO:0090304 nucleic acid metabolic process
2.28 1.92e-17 GO:0016070 RNA metabolic process
2.20 1.20e-16 GO:0010467 gene expression
1.66 5.50e-16 GO:0044260 cellular macromolecule metabolic process
1.90 1.64e-15 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
3.70 1.00e-13 GO:0016032 viral reproduction
1.44 5.27e-12 GO:0044237 cellular metabolic process
1.51 2.12e-11 GO:0043170 macromolecule metabolic process
1.70 3.33e-11 GO:0034641 cellular nitrogen compound metabolic process
1.65 4.37e-10 GO:0006807 nitrogen compound metabolic process
3.60 2.81e-09 GO:0006412 translation
6.06 9.18e-08 GO:0006415 translational termination
1.88 1.25e-07 GO:0034645 cellular macromolecule biosynthetic process
5.35 1.36e-07 GO:0032984 macromolecular complex disassembly
5.35 1.36e-07 GO:0034623 cellular macromolecular complex disassembly
1.35 2.49e-07 GO:0044238 primary metabolic process
1.86 2.54e-07 GO:0009059 macromolecule biosynthetic process
1.31 3.89e-07 GO:0008152 metabolic process
2.67 3.97e-07 GO:0016071 mRNA metabolic process
5.48 6.20e-07 GO:0043241 protein complex disassembly
5.48 6.20e-07 GO:0043624 cellular protein complex disassembly
5.65 2.79e-06 GO:0019080 viral genome expression
5.65 2.79e-06 GO:0019083 viral transcription
2.42 2.84e-06 GO:0006396 RNA processing
2.05 1.58e-05 GO:0032774 RNA biosynthetic process
3.04 2.07e-05 GO:0008380 RNA splicing
3.62 3.83e-05 GO:0022411 cellular component disassembly
3.62 3.83e-05 GO:0071845 cellular component disassembly at cellular level
4.73 5.28e-05 GO:0006414 translational elongation
2.47 6.93e-05 GO:0034621 cellular macromolecular complex subunit organization
2.69 7.02e-05 GO:0006397 mRNA processing
1.56 8.49e-05 GO:0044267 cellular protein metabolic process
3.96 1.01e-04 GO:0031016 pancreas development
3.34 1.09e-04 GO:0033365 protein localization to organelle
4.27 1.28e-04 GO:0031018 endocrine pancreas development
1.56 1.85e-04 GO:0044249 cellular biosynthetic process
5.14 2.34e-04 GO:0006354 transcription elongation, DNA-dependent
2.02 3.37e-04 GO:0043933 macromolecular complex subunit organization
1.53 4.23e-04 GO:0009058 biosynthetic process
3.75 1.02e-03 GO:0019058 viral infectious cycle
2.17 1.48e-03 GO:0071822 protein complex subunit organization
2.25 1.77e-03 GO:0070727 cellular macromolecule localization
3.38 2.75e-03 GO:0022415 viral reproductive process
3.04 3.13e-03 GO:0071843 cellular component biogenesis at cellular level
2.21 3.76e-03 GO:0034613 cellular protein localization
1.77 6.23e-03 GO:0008104 protein localization
1.44 9.65e-03 GO:0071841 cellular component organization or biogenesis at cellular level
1.90 1.10e-02 GO:0046907 intracellular transport
4.60 1.37e-02 GO:0072594 establishment of protein localization to organelle
2.92 1.58e-02 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
2.92 1.58e-02 GO:0000398 nuclear mRNA splicing, via spliceosome
2.92 1.58e-02 GO:0022613 ribonucleoprotein complex biogenesis
2.29 1.80e-02 GO:0006886 intracellular protein transport
4.77 2.20e-02 GO:0006368 transcription elongation from RNA polymerase II promoter
2.85 2.37e-02 GO:0000375 RNA splicing, via transesterification reactions
2.06 3.30e-02 GO:0044265 cellular macromolecule catabolic process
1.62 3.68e-02 GO:0033036 macromolecule localization
2.89 4.74e-02 GO:0035270 endocrine system development
1.78 4.93e-02 GO:0015031 protein transport

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
1.26 9.10e-21 GO:0005622 intracellular
3.72 2.88e-19 GO:0030529 ribonucleoprotein complex
1.26 9.32e-19 GO:0044424 intracellular part
1.32 4.53e-18 GO:0043229 intracellular organelle
1.32 7.10e-18 GO:0043226 organelle
1.55 3.43e-17 GO:0005634 nucleus
1.35 7.96e-17 GO:0043231 intracellular membrane-bounded organelle
1.35 1.02e-16 GO:0043227 membrane-bounded organelle
1.94 6.63e-15 GO:0031974 membrane-enclosed lumen
1.96 6.88e-15 GO:0070013 intracellular organelle lumen
1.97 1.74e-14 GO:0044428 nuclear part
1.92 4.34e-14 GO:0043233 organelle lumen
2.01 1.14e-12 GO:0031981 nuclear lumen
1.44 7.15e-11 GO:0044446 intracellular organelle part
4.55 1.74e-10 GO:0005840 ribosome
1.42 4.65e-10 GO:0044422 organelle part
1.58 1.06e-09 GO:0032991 macromolecular complex
2.56 1.21e-06 GO:0005730 nucleolus
1.88 1.55e-06 GO:0005654 nucleoplasm
1.53 1.04e-05 GO:0043228 non-membrane-bounded organelle
1.53 1.04e-05 GO:0043232 intracellular non-membrane-bounded organelle
4.11 1.12e-05 GO:0005681 spliceosomal complex
5.98 1.74e-05 GO:0015934 large ribosomal subunit
4.93 2.22e-04 GO:0022626 cytosolic ribosome
1.71 2.81e-04 GO:0005739 mitochondrion
2.02 2.96e-04 GO:0044451 nucleoplasm part
2.96 4.03e-04 GO:0016604 nuclear body
4.61 5.08e-04 GO:0071013 catalytic step 2 spliceosome
1.17 6.76e-03 GO:0005737 cytoplasm
4.91 8.80e-03 GO:0015935 small ribosomal subunit
1.22 1.47e-02 GO:0044444 cytoplasmic part
1.06 1.82e-02 GO:0044464 cell part
1.06 1.85e-02 GO:0005623 cell
3.20 2.11e-02 GO:0016607 nuclear speck
2.91 2.39e-02 GO:0044445 cytosolic part
1.43 2.73e-02 GO:0005829 cytosol
5.88 4.30e-02 GO:0030532 small nuclear ribonucleoprotein complex

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
2.40 1.69e-09 GO:0003723 RNA binding
4.75 4.89e-09 GO:0003735 structural constituent of ribosome
1.55 4.15e-08 GO:0003676 nucleic acid binding
2.43 7.40e-03 GO:0008134 transcription factor binding
1.19 1.06e-02 GO:0005515 protein binding
4.78 3.26e-02 GO:0016251 general RNA polymerase II transcription factor activity